News

New article published

28 Jul 2021

Variability in the type and layer distribution of cortical Aβ pathology in familial Alzheimer's disease

Our Research Technician, Dr Nanet Willumsen recently published a paper in Brain Pathology about possible influences of APOE4 genotype and PSEN1 mutation type on Abeta deposition.

New article published

15 Jul 2021

Knock-in models related to Alzheimer's disease: synaptic transmission, plaques and the role of microglia

Our Project Officer, Dr Diana Benitez recently published a paper in Molecular Neurodegeneration journal about how increased glutamate release probability is similar across knock-in and transgenic models of Alzheimer's disease.

UPDATE: Biogen TREM2 project

12 Jul 2021

Another milestone, experiments completed!

We are thrilled to announce that our team successfully completed all the single-cell RNAseq, bulk RNAseq, immunohistochemistry and genotyping experiments last week! We are trying to characterise cell-type-specific transcriptomic changes in TREM2var human brains with Alzheimer's Disease. Stay tuned to hear about our preliminary results!

Neurogenomics Seminars

30 Jun 2021

Tuesday 13th of July: Dr Topher Hübel

From Kings College London, Genetics of eating disorders, behaviours and cognitions. Zoom meeting time: 15:00-16:00h (UK). Contact us for the zoom access link.

Neurogenomics Seminars

30 Jun 2021

Tuesday 13th of July: Dr Topher Hübel

From Kings College London, Genetics of eating disorders, behaviours and cognitions. Zoom meeting time: 15:00-16:00h (UK). Contact us for the zoom access link.

Neurogenomics Seminars

24 Jun 2021

Tuesday 29th of June 2021: Dr Marek Bartosovic

From the Karolinska Institute, Single-cell CUT&Tag profiling of histone modifications in the mouse brain.  Zoom meeting time: 15:00-16:00h (UK). Contact us for the zoom access link.

Neurogenomics Seminars

10 Jun 2021

Tuesday 15th of June 2021: Dr Sarah Dick & Homaira Hamidzada

From the University of Toronto, Cross-tissue organization of resident macrophage subsets. Zoom meeting time: 15:00-16:00h (UK). Contact us for the zoom access link.

Brain samples from the Netherlands Brain Bank are coming to the MAP!

03 Jun 2021

UPDATE: The effects of experimental delay on freshly resected tissue for single nuclei transcriptomics

We are thrilled to confirm that our tissue request to receive samples from the Netherlands Brain Bank has been approved!

Neurogenomics Seminars

25 May 2021

Tuesday 1st of June 2021: Dr William Lai

From Cornell University, Screening of PCRP transcription factor antibodies in ChIP-exo.  Zoom meeting time: 15:00-16:00h (UK). Contact us for the zoom access link.

Neurogenomics Seminars

10 May 2021

Tuesday 18th of May 2021: Dr Stefano Berto

From the Medical University of South Carolina, Imaging genomics of the human brain: insights into the human memory.  Zoom meeting time: 15:00-16:00h (UK). Contact us for the zoom access link.