Our Research Technician Callum Muirhead is leaving the MAP team

After more than two years in the MAP team, Callum Muirhead will take all his expertise in Imaging Mass Cytometry to Kings College London where he will become Senior Laboratory Technician. He organised several social meetings for the UK DRI and he will be missed. All the best Callum!

New Bioinformatician

Our warmest welcome to Michael Thomas. He will be part of our Bioinformaticians team, now that all our results are coming, we need a team to put all of those together! It is great to have all your expertise on board Michael!

New Data manager

Enoch Newman has joined our team as Data manager. Enoch has  several years of experience as Software engineer and designer, he is now bringing his best skills to handle huge amounts of data and results from our multiple projects. Welcome to the team!

The effects of the ABCA7/BIN1 on the pathology and gene expression in Alzheimer’s Disease.

Next year we will start an exciting project to characterise the multi-'omic changes in microglia, astrocytes and neurons alongside changes in pathology with ABCA7 and BIN1 variants.

Mechanisms contributing to differential genetic risks for TREM2 R47H and R62H variants in Alzheimer’s Disease

You can read the pre-print in MedRxiv here. This research characterised neuropathology and transcriptomic responses in heterozygotes for R47H-R62H TREM2 variant alleles and for c

Work with fixed tissue is kicking off

We are thrilled to announce that our team has made such a great progress with the Multi-omics Atlas Project! We are soon receiving tissue from the Edinburgh Brain and Tissue Bank; our lab technicians are ready to process fixed human brain samples.

Multi-omics analyses for human Alzheimer’s disease research

We are glad to welcome Eléonore Schneegans to the MAP team! Her PhD project involves looking at molecular profiles of neuroprotective versus neurotoxic microglia which are thought to be potential therapeutic targets for AD.

Diverse human astrocyte and microglial transcriptional responses to Alzheimer’s pathology

This new publication highlights responses of both astrocytes and microglia for pathological protein clearance and inflammation, as well as glial transcriptional diversity in Alzheimer`s Disease.

scFlow: A Scalable and Reproducible Analysis Pipeline for Single-Cell RNA Sequencing Data

Our team published some exciting results in BioRxiv where they demonstrate the functionality of the analysis pipeline from sparse-matrix quality control through to insight discovery with examples of four datasets.

Here we have some members of the MAP team enjoying dinner just before the Christmas break. Check out our photo!