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FROM OUR TEAM

 

Recent publications from the team are highlighted here.

Single nuclear transcriptional signatures of dysfunctional brain vascular homeo…
Mechanisms contributing to differential genetic risks for TREM2 R47H and R62H v…
MungeSumstats: a Bioconductor package for the standardization and quality contr…
Diverse human astrocyte and microglial transcriptional responses to Alzheimer’s…
scFlow: A Scalable and Reproducible Analysis Pipeline for Single-Cell RNA Seque…
Probablilistic cell typing enables fine mapping of closely related cell types i…
​​​​​​​Genome-wide analysis of insomnia in 1,331,010 individuals identifies new…
Genome-wide meta-analysis identifies new loci and functional pathways influenci…
Genetic risk variants for brain disorders are enriched in cortical H3K27ac doma…
A histone acetylome-wide association study of Alzheimer's disease identifies di…

FROM THE COMMUNITY

 

Multi-'omics, and in particular transcriptomics, is driving our understanding of Alzheimer's Disease at a rapid rate.  Below are some key recent publications in the field.
Molecular characterisation of selectively vulnerable neurons in Alzheimer's Dis…
A taxonomy of transcriptomic cell types across the isocortex and hippocampal fo…
Single-cell multi-omic integration compares and contrasts features of brain cel…
Profiling microglia from AD donors and non-demented elderly in acute human post…

OUR CONFERENCE ABSTRACTS

 
Attendance at international and national meetings:
AAIC2023_ Glial and neuronal mechanisms contributing to diff_Fancy et al.pdf
BNA 2023_Neuronal selective vulnerability_Caramello et al.pdf
ADPD 2023_Glial senescence in Alzheimer's Disease_Fancy et al.pdf
ADPD23 Transcriptomic dissection of impaired angiogenesis and BBB function in AD_Tsartsalis et a.pdf
ADPD23 Mechanisms contributing to differential genetic risks in TREM2_Fancy et al.pdf
Connectome 2022_Imaging mass cytometry of neuronal microenvironment_Chau et al.pdf
Connectome 2022_GeoMx a revolution for spatial transcriptomics in AD_Adair et al.pdf
FENS 2022_The impact of Alzheimer’s Disease on the human synaptome_Griffiths et al.pdf
AANP 2022_Widespread cerebrovascular dysfunction in AD_Asby et al.pdf

OUR CONFERENCE POSTERS 

Glial and neuronal responses contributing to differential risks_Fancy et al.pdf
GeoMX a revolution for spatial transcriptomics in AD - Adair et al.pdf
Glial senescence in AD - Fancy et al.pdf
Imaging mass cytometry of neuronal microenvironment - Chau et al.pdf
Impact of AD on human synaptome - Griffiths et al.pdf
Imaging mass cytometry of selective neuronal vulnerability - Caramello et al.pdf
Impaired angiogenesis and BBB function in AD - Tsartsalis et al.pdf
AAIC2023